Paul Ince makes two changes for the top of the table clash with Norwich City.
Looking for a third successive win, in-form Canaries come to Berkshire unbeaten in eight.
With another game, away to Queens Park Rangers, on Friday- the Royals cannot afford to lose any more players to injury, joining the likes of Femi Azeez, Scott Dann and Baba Rahman.
Captain Andy Yiadom, injured in a 3-1 win over Huddersfield Town on Saturday, misses out as Mamadou Loum and Tyrese Fornah come in from the start.
FULL TEAM: Lumley; Hoilett; Hutchinson; Holmes; McIntyre; Guinness-Walker; Loum; Fornah; Hendrick; Ince; Carroll
Lucas Joao, top scorer for the Royals, is the other player to drop out- with a place on the bench.
Dean Smith makes one change to his Norfolk-based outfit from their 1-0 win over Blackpool, with Liam Gibbs replaced Onel Hernandez.
FULL TEAM: Krul; Aarons; Bryam; Omobamidele; Hanley; Ramsey; Pukki; McLean; Sargent; Nunez; Gibbs
Comments: Our rules
We want our comments to be a lively and valuable part of our community - a place where readers can debate and engage with the most important local issues. The ability to comment on our stories is a privilege, not a right, however, and that privilege may be withdrawn if it is abused or misused.
Please report any comments that break our rules.
Read the rules here